Résumé
Background and objectives: Among placental mammals, females undergo immunological shifts during pregnancy to accommodate the fetus (i.e. fetal tolerance). Fetal tolerance has primarily been characterized within post-industrial populations experiencing evolutionarily novel conditions (e.g. reduced pathogen exposure), which may shape maternal response to fetal antigens. This study investigates how ecological conditions affect maternal immune status during pregnancy by comparing the direction and magnitude of immunological changes associated with each trimester among the Tsimane (a subsistence population subjected to high pathogen load) and women in the USA.
Référence
Carmen Hové, Benjamin C. Trumble, Amy Anderson, Jonathan Stieglitz, Hillard Kaplan, Michael Gurven et Aaron D. Blackwell, « Immune function during pregnancy varies between ecologically distinct populations », Evolution, Medicine, and Public Health, n° 1, juillet 2020, p. 114–128.
Voir aussi
Publié dans
Evolution, Medicine, and Public Health, n° 1, juillet 2020, p. 114–128